Cassava Sciences (NASDAQ:SAVA – Get Free Report) and Reviva Pharmaceuticals (NASDAQ:RVPH – Get Free Report) are both small-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their valuation, analyst recommendations, dividends, earnings, institutional ownership, risk and profitability.
Analyst Ratings
This is a breakdown of current ratings for Cassava Sciences and Reviva Pharmaceuticals, as provided by MarketBeat.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Cassava Sciences | 1 | 1 | 0 | 0 | 1.50 |
| Reviva Pharmaceuticals | 1 | 0 | 7 | 1 | 2.89 |
Cassava Sciences currently has a consensus price target of $2.00, suggesting a potential downside of 8.26%. Reviva Pharmaceuticals has a consensus price target of $3.86, suggesting a potential upside of 1,156.81%. Given Reviva Pharmaceuticals’ stronger consensus rating and higher possible upside, analysts clearly believe Reviva Pharmaceuticals is more favorable than Cassava Sciences.
Earnings and Valuation
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Cassava Sciences | N/A | N/A | -$24.34 million | ($2.19) | -1.00 |
| Reviva Pharmaceuticals | N/A | N/A | -$29.92 million | ($0.46) | -0.67 |
Cassava Sciences is trading at a lower price-to-earnings ratio than Reviva Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.
Profitability
This table compares Cassava Sciences and Reviva Pharmaceuticals’ net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Cassava Sciences | N/A | -63.39% | -49.81% |
| Reviva Pharmaceuticals | N/A | -20,501.80% | -187.50% |
Volatility and Risk
Cassava Sciences has a beta of -1.08, meaning that its share price is 208% less volatile than the S&P 500. Comparatively, Reviva Pharmaceuticals has a beta of -0.02, meaning that its share price is 102% less volatile than the S&P 500.
Institutional & Insider Ownership
38.1% of Cassava Sciences shares are held by institutional investors. Comparatively, 63.2% of Reviva Pharmaceuticals shares are held by institutional investors. 2.4% of Cassava Sciences shares are held by company insiders. Comparatively, 8.9% of Reviva Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.
Summary
Reviva Pharmaceuticals beats Cassava Sciences on 9 of the 12 factors compared between the two stocks.
About Cassava Sciences
Cassava Sciences, Inc., a clinical stage biotechnology company, develops drugs for neurodegenerative diseases. Its lead therapeutic product candidate is simufilam, a small molecule drug, which is completed Phase 2 clinical trial; and investigational diagnostic product candidate is SavaDx, a blood-based biomarker/diagnostic to detect Alzheimer's disease. The company was formerly known as Pain Therapeutics, Inc. and changed its name to Cassava Sciences, Inc. in March 2019. Cassava Sciences, Inc. was incorporated in 1998 and is based in Austin, Texas.
About Reviva Pharmaceuticals
Reviva Pharmaceuticals Holdings, Inc., a biopharmaceutical company, discovers, develops, and commercializes next-generation therapeutics for diseases targeting unmet medical needs in the areas of central nervous system, respiratory, inflammatory, and cardiometabolic diseases. The company's lead product candidate comprises brilaroxazine (RP5063) for the treatment of various neuropsychiatric indications, including schizophrenia, bipolar disorder, major depressive disorder, attentiondeficit/hyperactivity disorder, behavioral and psychotic symptoms of dementia and Alzheimer's disease, and Parkinson's disease psychosis; in clinical development respiratory indications, such as pulmonary arterial hypertension and idiopathic pulmonary fibrosis; and in preclinical development for the treatment of psoriasis. It is also developing RP1208 for the treatment of depression and obesity. Reviva Pharmaceuticals Holdings, Inc. was founded in 2018 and is headquartered in Cupertino, California.
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